US Secretary of State Hillary Clinton and Egyptian foreign minister Mohammed Kamel Amr announce an agreement of a cease-fire in Gaza. NBC's Martin Fletcher reports.
By NBC News staff and wire reports
Updated at 2:17 p.m. ET: Israel and Hamas agreed to a cease-fire Wednesday, ending eight days of fighting that killed more than 140 Palestinians and five Israelis.
?The United States welcomes the agreement today for the cease-fire in Gaza," U.S. Secretary of State Hillary Clinton said at a news conference alongside Egyptian Foreign Minister Mohamed Kamel Amr.?"This is a critical moment for the region."
The cease-fire started at 9 p.m. Cairo time (2 p.m. ET).
Clinton thanked Egypt's Islamist President Mohammed Morsi for his mediation efforts and pledged to work with partners in the region "to consolidate this progress, improve conditions for the people of Gaza, provide security for the people of Israel."
In Jerusalem, Israeli Prime Minister Benjamin Netanyahu confirmed the agreement, adding that he had spoken with President Barack Obama and had agreed to fight together against "weapons of terror."
"Israel cannot sit with its arms folded against its enemies," he said in a news conference.
Netanyahu paid tribute to U.S. diplomacy and Morsi's leadership, but also to Israel's resolve and the armed forces.
"I am proud to be your prime minister," he said.
According to the cease-fire agreement: Israel will stop attacks on Gaza by land, sea and air and stop incursions and targeted assassinations; Palestinian factions will stop hostilities from the Gaza Strip against Israel; Israel will ease the movement of people and goods at border-crossing areas.
Egypt is the "sponsor" of the cease-fire agreement.
In comments following the cease-fire announcement, Israeli Defense Minister Ehud Barak said the army had been effective, achieving maximum destruction to Hamas with minimum loss of civilian life.
Barak added that the Iron Dome defense system was "an exceptional success," knocking down 500 incoming missiles.
Hours before the announcement, an explosion on a bus in Tel Aviv injured 19 people, three of them seriously, an official told NBC News.
Tel Aviv police spokesman Micky Rosenfeld told the U.K.'s Sky News that the bus blast took place in the heart of the city and that the surrounding area had been cordoned off as police searched for suspects.
"This was a terrorist attack," Ofir Gendelman, a spokesman for Netanyahu, told Reuters.
The White House condemned the attack as "outrageous."?In a statement, it reaffirmed the United States' "unshakable commitment to Israel's security and our deep friendship and solidarity with the Israeli people."
A bomb ripped through a bus in Tel Aviv on Wednesday, wounding at least 16 people. NBC's Stephanie Gosk reports.
Hamas spokesman Sami Abu Zuhri praised the bombing, but stopped short of claiming responsibility.
"Hamas blesses the attack in Tel Aviv and sees it as a natural response to the Israeli massacres...in Gaza," he told Reuters. "Palestinian factions will resort to all means in order to protect our Palestinian civilians in the absence of a world effort to stop the Israeli aggression."
More photos: Explosion hits bus in Tel Aviv
Sweet cakes were handed out in celebration of the blast in Gaza's main hospital, which has been inundated with wounded from the round-the-clock Israeli bombing and shelling, Reuters reported.?Celebratory gunfire rang out in Gaza City when local radio stations reported the news.
The last time Israel's commercial capital was hit by a serious bomb blast was in April 2006, when a Palestinian suicide bomber killed 11 people at a sandwich stand near the city's old central bus station.
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Like most Western powers, Washington shuns Hamas as an obstacle to peace and has blamed it for the Gaza conflagration.
A U.N. Security Council statement condemning the conflict was blocked on Tuesday by the United States, which complained that it "failed to address the root cause" -- the Palestinian rockets.
Meanwhile, the head of Iran's powerful Revolutionary Guard has disclosed his country has given fighters in Gaza the ability to produce longer-range missiles on their own, without direct shipments.?The comments, by Gen. Mohammad Ali Jafari, quoted by the semi-official ISNA news agency, offer some of the clearest insights on Iran's weapons support for Hamas.
Previously, Iran denied it directly supplied Hamas with the Fajr-5 rockets being fired at Israel in recent days.
NBC's Lawahez Jabari, Ian Johnston and Andy Eckardt, Reuters and The Associated Press contributed to this report.
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Two sides exchange deadly airstrikes, rocket attacks.
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